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A DNA analysis has found out that the plague bacteria which caused the Black Death in the 14th century was a very recent mutation - it did not develop before 1282. This also means that the Justinian plague must have been caused by another plague bacterium or an altogether different pathogenic organism.
Pest-Genom entziffert. Am Anfang war der Schwarze Tod
Stefan (Literary references to the discussed topics are always appreciated.)
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This is interesting. Over the summer I read a number of articles on the Antonine Plague, including several that tried to match Galen's description with the known symptoms of diseases we know today. The general consensus was smallpox, but that was only the best available choice from today's diseases, and many of Galen's symptoms didn't match. A few writers suggested that it was something different. The diseases that affected the ancients may have been quite a bit different from what modern medicine knows today.